PREMIUM TIME REVERSE CREAM (Face&Neck) 30ml

MAIN ACTIVE INGREDIENTS:

• NIACINAMIDE: Protects against sun damage. Niacinamide can concurrently rebuild healthy skin cellswhile also protecting them from damage caused by ultraviolet rays. Treats hyperpigmentation andcan be helpful in lightening dark spots. Research has found that it is helpful in reducing some signs ofsun damage that come with aging. This includes fine lines and wrinkles. Protects against oxidativestress. Niacinamide helps build cells in the skin while also protecting them from environmental stresses,such as sunlight, pollution, and toxins.
• HYALURONIC ACID (LMWHA): Hyaluronic acid has many functions throughout the body, especially inthe connective tissue. In the skin, some of its known roles are the following: Holding moisture.Increasing viscosity and reducing permeability of extracellular fluid. Contributing to mechanicalresilience and suppleness of the skin. Regulation of tissues repair. Regulation of movement andproliferation of cells. Regulation of immune and inflammatory responses
• SALICYLIC ACID: Salicylic acid improves the skin’s appearance, reduces blemishes and helps to preventblackheads and breakouts. Penetrates deep into pores. Loosens dead skin cells. Clears clogged pores. Reduces inflammation and redness. Helps to break down comedones.
• SKINECTURA: rapidly decreases the appearance of wrinkles (face and neck) and sagging skin withbuilding effect over time. This preservative-free & ecofriendly ingredient is a flower nectar for youngerskin structure. It increases tenascin-X synthesis to rebuild skin architecture. It is a certified organic botanical extract standardized in fructose & rutin content. It increases the secretion of structural proteins, collagen and elastin. It rapidly decreases the appearance of wrinkles after 1 hr with continuous improvement over 28 days. It is a natural multi-target and innovative ingredient that offers a rapid and long-lasting unique approach to the passage of time providing healthier, younger, and more beautiful looking skin.
• TENS’UP: is an innovative active ingredient with a marked lifting and tightening effect. Immediatelycauses lifting effect to the skin and visibly smooths wrinkles. Tens’Up and Retinol show comparableactivity. Increases collagen synthesis with wrinkle-replenishing effect. The immediate lifting ortightening action of the skin surface is a cosmetic property that exerts macromolecules such ascollagen, chitosan, keratin, hyaluronic acid, biopolymers and others. The mechanism of action of thesemolecules is to exert sufficient mechanical tension on the skin to smooth the cutaneous surface andprovide a smooth and resplendent appearance instantly. These macromolecules form a surface filmthat smoothes the skin, erases wrinkles and expression lines, and provides a more radiant andluminous appearance. The prolongation of this tightening effect depends exclusively on the film itself.Its dual action makes it possible to obtain ”flash” products with anti-ageing properties.
• ACETYL HEXAPEPTIDE-8: also known as “botox in a jar.” This peptide delivers impressive results whentargeting fine lines and wrinkles with water-binding properties to help restore the skin’s health andmake the barrier full functioning.
• TOCOPHERYL ACETATE: It offers significant antioxidant properties to help defend from pollution andother environmental stressors that would otherwise weaken skin, causing unwanted changes.
• UNICLAY: biotech ingredient is a fermentation-based extract derived from a clay microorganism thatmimics the effects of clay on the skin; offers cleaner, smoother and more beautiful skin for allethnicities and improved sense of well-being.

Referenser

1. How Much Do We Really Know About Our Favorite Cosmeceutical Ingredients? Jacquelyn Levin, DO and Saira B.Momin, DO. J Clin Aesthet Dermatol. 2010 Feb; 3(2): 22–41.
2. Superior Efficacy of an Herbal-based Cosmeceutical Compared With Common Prescription and Cosmetic AntiagingTherapies. Carl R Thornfeldt, Ronald L Rizer. J Drugs Dermatol. 2016 Feb;15(2):218-23.
3. Bioactive compounds from natural resources against skin aging. Pulok K. Mukherjeea,∗, Niladri Maitya, Neelesh K. Nemaa, Birendra K. Sarkarb. a School of Natural Product Studies, Department of Pharmaceutical Technology,Jadavpur University, Kolkata 700032, India
4. The Use of Botanical Extracts as Topical Skin-Lightening Agents for the Improvement of Skin PigmentationDisorders. Wenyuan Zhu1 and Jie Gao. 1Journal of Investigative Dermatology Symposium Proceedings (2008) 13, 20–24; doi:10.1038/jidsymp.2008.8
5. Hyaluronic acid: A key molecule in skin aging. Dermatoendocrinol. 2012 Jul 1; 4(3): 253–258. doi:10.4161/derm.21923. Eleni Papakonstantinou, Michael Roth, George Karakiulakis.
6. Type VI collagen microfibrils: evidence for a structural association with hyaluronan. J Cell Biol. 1992;118:979-90.Kielty CM, Whittaker SP, Grant ME, Shuttleworth CA.
7. 1456 Tensor effect of anigozanthos flavidus flower extract: Modulation of tenascin-X to regenerate the skin.Jonven Janet Attia, University of Rochester. M. Shortt. I. Lacasse. Estelle Loing. May 2018. Journal of InvestigativeDermatology 138(5):S247. DOI:10.1016/j.jid.2018.03.1474
8. Cichorium intybus root extract: A ”vitamin D-like” active ingredient to improve skin barrier function. J DermatologTreat, 2017 Feb;28(1):78-81. doi: 10.1080/09546634.2016.1178695. Epub 2016 May 10. P M B G Maia Campos, DG Mercurio, M O Melo, B Closs-Gonthier.
9. Evaluation of the antioxidative capability of commonly used antioxidants in dermocosmetics by in vivo detectionof protein carbonylation in human stratum corneum. J Photochem Photobiol B. (2012) Tsai FJ, et. al.
10. In vitro skin penetration of acetyl hexapeptide-8 from a cosmetic formulation. Cutan Ocul Toxicol. 2015Mar;34(1):46-52. doi: 10.3109/15569527.2014.894521. Epub 2014 Apr 22. Margaret E K Kraeling 1 , WanlongZhou, Perry Wang, Oluwatosin A Ogunsola.