PREMIUM DERMO CORRECTIVE CREAM (SPF50) 30ml

SOME MAIN ACTIVE INGREDIENTS:

• ZINK GLUCONATE: Speed wound healing and prevent scarring by assisting the body in processing essential fatty acids used by the skin for healing.
• PANTHENOL: A skin protectant, provide relief for dry and irritated skin. Significantly improve skin scaling, roughness, redness, cracks and itching. Reduce UV-induced damage to keratinocytes and fibroblast.
• SOY ISOFLAVONES: Prevent melanin pigments from adhering to skin cells and is effective against hyperpigmentation caused by sun damage.
• TITANIUM DIOXIDE： Physical sunscreen, protection against UVA/UVB
• OCTYL METHOXY CINNAMATE: Chemical sunscreen, protection against UVA/UVB.
• DIETHYLAMINO HYDROXYBENZOYL HEXYL BENZOATE: Chemical sunscreen, long term protection against UVA.
• ASCORBYL GLUCOSIDE: (Stable form of Vitamin-C) Long-term protection against formation of melanin, lightening of dark spots.
• 3-O-ETHYL ASCORBIC ACID: (Stable form of Vitamin-C) To promote the formation of collagen, lifting, enhance elasticity and lesser wrinkles. Lesser the formation of melanin and control the dark spots, to achieve whitening effectively.
• NIACINAMIDE: Suppresses melanin from reaching the surface of the skin and protects the skin from further UV damage.
• LEPIDIUM SATIVUM SPROUT EXTRACT: inhibits pigmentation by targeting the neutralization of reactive oxygen species and the inhibition of α-MSH, a natural hormone.
• AESCULUS HIPPOCSATANUM SEED EXTRACT: strengthen fragile capillaries, is used for its venotonic effect, vascular protection, anti-inflammatory and free radical scavenging properties
• AMMONIUM GLYCYRRHIZATE: anti-inflammatory, anti-irritant and soothing properties.
• MICA: Natural pigment from minerals, adjust the skin tone automatically.
• TOCOPHERYL ACETATE: Strong anti-oxidant
• GLYCOSYL TREHALOSE: Studies show that it can activate and protect the cell against UV.
• HYALURONIC ACID (LMWHA): Deep moisturizing effect
• DIPEPTIDE DIAMINOBUTYROYL BENZYLAMIDE DIACETATE (SNAKE NEURO PEPTIDE): Control muscle contractions (mimical wrinkles), gives the skin less wrinkle depth and increase skins smoothness.

References:

1. Medicinal plants used in treatment of inflammatory skin diseases. Postepy Dermatol Alergol. 2013 Jun; 30(3): 170–177. Published online 2013 Jun 20. doi: 10.5114/pdia.2013.35620 PMCID: PMC3834722 (Renata Dawid-Pać)
2. Bioactive compounds from natural resources against skin aging. Pulok K. Mukherjeea,∗, Niladri Maitya, Neelesh K. Nemaa, Birendra K. Sarkarb. a School of Natural Product Studies, Department of Pharmaceutical Technology, Jadavpur University, Kolkata 700032, India
3. The Use of Botanical Extracts as Topical Skin-Lightening Agents for the Improvement of Skin Pigmentation Disorders. Wenyuan Zhu1 and Jie Gao. 1Journal of Investigative Dermatology Symposium Proceedings (2008) 13, 20–24; doi:10.1038/jidsymp.2008.8
4. Titanium dioxide in our everyday life; is it safe? Radiol Oncol. 2011 Dec; 45(4): 227–247. Published online 2011 Nov 16. doi: 10.2478/v10019-011-0037-0. PMCID: PMC3423755. Matej Skocaj,1 Metka Filipic,2 Jana Petkovic,2 and Sasa Novak1
5. Vitamin C in Dermatology. Indian Dermatol Online J. 2013 Apr-Jun; 4(2): 143–146. doi: 10.4103/2229-5178.110593. PMCID: PMC3673383. Pumori Saokar Telang.
6. A novel vitamin C analog, 2-O-(beta-D-Glucopyranosyl)ascorbic acid: examination of enzymatic synthesis and biological activity. J Biosci Bioeng. (2005) Toyada-Ono Y, et. al.
7. In vitro and in vivo prolonged biological activities of novel vitamin C derivative, 2-O-alpha-D-glucopyranosyl-L-ascorbic acid (AA-2G), in cosmetic fields. J Nutr Sci Vitaminol (Tokyo). (1998) Kumano Y, et. al.
8. Ascorbic acid 2-O-alpha-glucoside-induced redox modulation in human keratinocyte cell line, SCC: mechanisms of photoprotective effect against ultraviolet light B. Biol Pharm Bull. (1997) Miyai E, et. al.
9. Evaluation of the antioxidative capability of commonly used antioxidants in dermocosmetics by in vivo detection of protein carbonylation in human stratum corneum. J Photochem Photobiol B. (2012) Tsai FJ, et. al.
10. Antioxidant properties of 2-O-beta-D-glucopyranosyl-L-ascorbic acid. Biosci Biotechnol Biochem. (2008) Takebayashi J, et. al.
11. Comparative evaluation of the antioxidant effects of the natural vitamin C analog 2-O-β-D-glucopyranosyl-L-ascorbic acid isolated from Goji berry fruit. Arch Pharm Res. (2011) Zhang Z, et. al.
12. Ascorbic acid 2-O-alpha-glucoside, a stable form of ascorbic acid, rescues human keratinocyte cell line, SCC, from cytotoxicity of ultraviolet light B. Biol Pharm Bull. (1996) Miyai E, et. al.
13. Ultrasound enhanced skin-lightening effect of vitamin C and niacinamide. Skin Res Technol. (2006) Hakozaki T, et. al.
14. Effects of vitamin C on dark circles of the lower eyelids: quantitative evaluation using image analysis and echogram. Skin Res Technol. (2009) Ohshima H, et. al.
15. The in vitro absorption of microfine zinc oxide and titanium dioxide through porcine skin. Toxicol In Vitro. 2006;20:301-7. Gamer AO, Leibold E, van Ravenzwaay B.
16. Hyaluronan fragments induce cytokine and metalloprotease upregulation in human melanoma cells in part by signalling via TLR4. Exp Dermatol. 2008;17:100-7. Voelcker V, Gebhardt C, Averbeck M, Saalbach A, Wolf V, Weih F, Sleeman J, Anderegg U, Simon J.
17. Type VI collagen microfibrils: evidence for a structural association with hyaluronan. J Cell Biol. 1992;118:979-90. Kielty CM, Whittaker SP, Grant ME, Shuttleworth CA.